产品货号：
GS4685
中文名称：
重组小鼠IL-22
英文名称：
Recombinant Murine Interleukin-22
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 16.6kDa,a single non-glycosylated polypeptide chain containing 146 amino acids.
储存条件：冷冻（-20℃）
概述
IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.Recombinant mouse interleukin-22 contains 147 amino acids and it has approximately 81%and 92%amino acid sequence identity with human and rat IL-22.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠IL-22，IL-22, Murine，Recombinant Murine Interleukin-22
储存条件：冷冻（-20℃）
概述
IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10,IL-19,IL-20,IL-22,IL-24 and IL-26.Members of this family share partial homology in their amino acid sequences,but they are dissimilar in their biological functions.Produced by T lymphocytes and dendritic cells,IL-10 contributes to the inflammatory response in vivo.IL-22 signals through CRF2-4 and IL-22.It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems.Recombinant mouse interleukin-22 contains 147 amino acids and it has approximately 81%and 92%amino acid sequence identity with human and rat IL-22.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞96%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.2ng/ml,corresponding to a specific activity of>5.0×106 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 1×PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuIL-22 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | LPVNTRCKLE VSNFQQPYIV NRTFMLAKEA SLADNNTDVR LIGEKLFRGV SAKDQCYLMK QVLNFTLEDV LLPQSDRFQP YMQEVVPFLT KLSNQLSSCH ISGDDQNIQK NVRRLKETVK KLGESGEIKA IGELDLLFMS LRNACV |
相关搜索：重组小鼠IL-22，IL-22, Murine，Recombinant Murine Interleukin-22